Honora was the daughter of Owen McCarthy Reagh but her mother is unknown. The date and place of her birth have not been found.
She had two marriages/partners. Her first husband was sir Edmond Fitz-John FitzGerald. They were married, but the date and place have not been found. Their seven known children were Ellen (?-?), Thomas (?-?), sir John (?-?), Elenor (?-?), Isabel (?-?), Honora Oge (?-?) and Any (?-?).
Her second husband was sir James FitzJames FitzGerald. They were married, but the date and place have not been found. They had no known children.