Isabel was the daughter of unknown parents. The date and place of her birth have not been found.
Her husband was Pedro Manrique de Lara. They were married, but the date and place have not been found. They had no known children.
Note 1
Tochter von Diego Fernández de Quiñones, Señor de Luna, Quiñones, Laguna y el Infantazgo de Valdetorio, Merino mayor de Asturias, und María de Toledo